Gene Moore has been in professional baseball since 1929, making his start with the Midland Club of the West Texas League. He played with various other minor league clubs until he was signed up by the Cincinnati Reds in 1931, who in turn farmed him out. He became the property of the St. Louis Cardinals at the end of the 1933 season, who farmed him out to Columbus, recalling him in 1935. Gene was again farmed out to the Rochester Club in 1935, collecting 144 hits for them and wound up the season with a batting average of .324. On the strength of this, Moore became the property of the Boston Bees and was their regular outfielder until the end of the 1938 season when he was traded to the Brooklyn Dodgers along with Ira Hutchinson for Buddy Hassett and Jimmy Outlaw. Moore's seven-year major-league record shows that he has taken part in 380 games, collecting 415 hits for a batting average of .286.